Science moves us, and we move Science.

IDOR was born from the desire to build solid scientific knowledge in the health and medical field. Since its inception, it has been working on different topics, with a multidisciplinary team of researchers and partnerships with major institutions in Brazil and around the world. As a result, our team has published hundreds of articles in international scientific journals.

IDOR played a prominent role, for example, in the multi-institutional effort that established the causal relationship between the Zika virus and the increased occurrence of microcephaly in Brazil in 2016. It was also the pioneer in Latin America in the creation of reprogrammed stem cells from the urine of patients, a promising noninvasive method. Meet below our areas of research:

INTENSIVE CARE MEDICINE

IDOR coordinates and participates in multicentered studies in intensive care medicine, whose primary objective is to evaluate the treatment of critical patients and to propose solutions to improve it. Among the main research themes in this area are sepsis; epidemics and emerging diseases; bacterial resistance in hospital spaces; hospital death and efficiency analysis in health services.

Our team also researches more specific topics, such as providing intensive care to cancer and immunosuppressed patients, respiratory diseases in ICUs, and acute brain dysfunction and delirium in critically ill patients.

INTERNAL MEDICINE

In this area, our main objective is to understand liver, gastrointestinal, pulmonary and cardiac diseases to propose new diagnostic methods, prognostic markers, and potential therapeutic targets.

We conduct epidemiological, clinical, molecular, genetic, morphological, functional and imaging studies. Among the main themes of research, we study liver cirrhosis and its complications, nonalcoholic fatty liver disease, the relationships between inflammation and cancer, congenital heart diseases, genetic analysis of patients with cardiac channelopathy and noninvasive diagnoses of lung diseases, such as tuberculosis and acute lung injury.

 

NEUROSCIENCES

Neurologists, psychiatrists, psychologists, biologists and other IDOR specialists conduct investigations about the brain, considering its development and the different pathologies that can affect the central nervous system in search of new methods of diagnosis and treatments.

Tools of neuroimaging and cell reprogramming are used to investigate topics such as brain plasticity, human behavior, and emotions, neuropsychiatric diseases, and the impact of substances on brain functioning. We also develop computational tools for radiology and, together with the Center for Applied Neuropsychology (CNA) and the hospitals of Rede D’Or São Luiz (RDSL), we carry out clinical studies in the area of psychiatry and neurology.

 

ONCOLOGY

Our researchers work with excellence in both basic and clinical research, where patients can have firsthand access to developing therapies.

We have a partnership with the D’Or Oncology branch and its president, Dr. Paulo Hoff, who has expanded clinical research in this area to a national scope, throughout RDSL’s network. Currently, we develop activities in the centers of Rio de Janeiro, São Paulo, Brasília, and Salvador.

 

PEDIATRICS

We are interested in the study of child development in early childhood in its physical, motor, intellectual, affective, emotional and social aspects. We also look at particular subgroups, such as children with congenital Zika virus infection, and conduct studies related to health quality and human resources training in the field of pediatrics.

We develop research on topics such as respiratory diseases in children and adolescents – focusing on viral diseases, asthma, pneumonia and acute respiratory distress syndrome – and sepsis, including the condition epidemiology, diagnosis, and treatment in pediatrics health services.

 

CLINICAL AND SPONSORED RESEARCH

IDOR supports clinical initiatives of its researchers and also participates in multicenter studies developed by the pharmaceutical industry. These projects may involve other health institutions in Brazil and worldwide.

Researchers