{"id":28637,"date":"2026-07-08T12:14:49","date_gmt":"2026-07-08T15:14:49","guid":{"rendered":"https:\/\/ptbr.idor.org\/servicos\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/"},"modified":"2026-07-08T12:17:04","modified_gmt":"2026-07-08T15:17:04","slug":"servicos-diagnosticos-e-de-apoio-a-pesquisa","status":"publish","type":"page","link":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/","title":{"rendered":"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa"},"content":{"rendered":"\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t
\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\n

Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa<\/h1>\n <\/div>\n \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\n Home<\/a>\n \n <\/div>\n \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

“A dosagem plasm\u00e1tica da prote\u00edna pTau-217 representa um avan\u00e7o significativo no diagn\u00f3stico da Doen\u00e7a de Alzheimer e oferece um novo par\u00e2metro para avalia\u00e7\u00e3o e monitoramento de resposta aos agentes biol\u00f3gicos direcionados \u00e0s placas amiloides.”<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

O Desafio do Diagn\u00f3stico<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

A Doen\u00e7a de Alzheimer (DA) \u00e9 a principal causa de dem\u00eancia no mundo todo e, apesar da alta preval\u00eancia, seu diagn\u00f3stico continua sendo desafiador.<\/p>

Tradicionalmente baseado no estudo das manifesta\u00e7\u00f5es cl\u00ednicas, o diagn\u00f3stico da DA \u00e9 apoiado por exame de PET-CT com marcador espec\u00edfico (pouco acess\u00edvel) e por an\u00e1lises de prote\u00ednas do l\u00edquor (invasivo).<\/p>

Os custos e riscos inerentes a esses procedimentos impedem sua utiliza\u00e7\u00e3o em larga escala e se revelam obst\u00e1culos importantes ao diagn\u00f3stico precoce e \u00e0 avalia\u00e7\u00e3o de resposta \u00e0s terapias.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

Um Novo Biomarcador<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Estudo recente conduzido pelo IDOR, em parceria com a Universidade Federal do Rio de Janeiro, Neurolife e Queen’s University do Canad\u00e1, relacionou n\u00edveis plasm\u00e1ticos aumentados da prote\u00edna pTau-217 \u00e0 Doen\u00e7a de Alzheimer, o que n\u00e3o foi observado nas outras formas de dem\u00eancia. (1)<\/p>

Com base nestes resultados, a dosagem da prote\u00edna pTau-217 pode ser utilizada para facilitar o diagn\u00f3stico da DA.<\/strong> Al\u00e9m disso, seu n\u00edvel plasm\u00e1tico pode ser monitorado para acompanhamento da doen\u00e7a e avalia\u00e7\u00e3o de resposta ao tratamento.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

O Exame pTau-217<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

O exame, resultado da colabora\u00e7\u00e3o entre Instituto D’Or de Pesquisa e Ensino (IDOR), Rede D’Or e Laborat\u00f3rio Richet, \u00e9 um LDT (Laboratory Developed Test), validado por dados cient\u00edficos publicados em revista de grande impacto.<\/p>

A integra\u00e7\u00e3o entre pesquisa cient\u00edfica, pr\u00e1tica cl\u00ednica e rigor laboratorial garante ao teste pTau-217 alto padr\u00e3o de qualidade e confiabilidade.<\/p>

O teste \u00e9 realizado com a tecnologia SIMOA (Single Molecule Array) capaz de detectar prote\u00ednas em concentra\u00e7\u00f5es extremamente baixas, permitindo a testagem em uma amostra de sangue em lugar do l\u00edquor.(2)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

Principais Caracter\u00edsticas<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t
  • Exame realizado com uma pequena amostra de sangue;<\/li>
  • Tem alta sensibilidade e especificidade, compar\u00e1vel aos m\u00e9todos usuais (dosagem no l\u00edquor e PET-CT);<\/li>
  • R\u00e1pido, acess\u00edvel e pouco invasivo;<\/li>
  • Validado no Brasil pelo IDOR em parceria com a Rede D’Or e o Laborat\u00f3rio Richet.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
    \n\t\t\t\t\t
    \n\t\t\t\t
    \n\t\t\t\t\t\t\t
    \n\t\t\t
    <\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
    \n\t\t\t\t\t
    \n\t\t\t\t
    \n\t\t\t\t\t

    Indica\u00e7\u00f5es do Exame<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
    \n\t\t\t\t\t
    \n\t\t\t\t
    \n\t\t\t\t\t\t\t\t\t
    • Contribuir para o diagn\u00f3stico de pacientes com suspeita de DA;<\/li>
    • Par\u00e2metro de acompanhamento para evolu\u00e7\u00e3o da doen\u00e7a e resposta ao tratamento;<\/li>
    • Par\u00e2metro para sele\u00e7\u00e3o de participantes para ensaios cl\u00ednicos (screening de positivos\/negativos para amiloide);<\/li>
    • Indicador progn\u00f3stico, com n\u00edveis elevados se associando a pior desempenho cognitivo no futuro.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
      \n\t\t\t\t\t
      \n\t\t\t\t
      \n\t\t\t\t\t\t\t
      \n\t\t\t\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
      \n\t\t\t\t\t
      \n\t\t\t\t
      \n\t\t\t\t\t\t\t\t\t

      O IDOR est\u00e1 preparado para apoi\u00e1-lo em suas pesquisas.<\/p>

      Fale conosco:<\/strong><\/p>

      centralderelacionamento@idor.org<\/p>

      21 3883-6000<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

      \n\t\t\t\t\t
      \n\t\t\t\t
      \n\t\t\t\t\t\t\t
      \n\t\t\t
      <\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-28637","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nServi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa - IDOR - Instituto D'Or de Pesquisa e Ensino<\/title>\n<link rel=\"canonical\" href=\"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa - IDOR - Instituto D'Or de Pesquisa e Ensino\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/\" \/>\n<meta property=\"og:site_name\" content=\"IDOR - Instituto D'Or de Pesquisa e Ensino\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-08T15:17:04+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ptbr.idor.org\\\/servicos-diagnosticos-e-de-apoio-a-pesquisa\\\/\",\"url\":\"https:\\\/\\\/ptbr.idor.org\\\/servicos-diagnosticos-e-de-apoio-a-pesquisa\\\/\",\"name\":\"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa - IDOR - Instituto D'Or de Pesquisa e Ensino\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rededorsaoluiz.com.br\\\/instituto\\\/idor\\\/#website\"},\"datePublished\":\"2026-07-08T15:14:49+00:00\",\"dateModified\":\"2026-07-08T15:17:04+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ptbr.idor.org\\\/servicos-diagnosticos-e-de-apoio-a-pesquisa\\\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ptbr.idor.org\\\/servicos-diagnosticos-e-de-apoio-a-pesquisa\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ptbr.idor.org\\\/servicos-diagnosticos-e-de-apoio-a-pesquisa\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\\\/\\\/www.rededorsaoluiz.com.br\\\/instituto\\\/idor\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.rededorsaoluiz.com.br\\\/instituto\\\/idor\\\/#website\",\"url\":\"https:\\\/\\\/www.rededorsaoluiz.com.br\\\/instituto\\\/idor\\\/\",\"name\":\"IDOR - Instituto D'Or de Pesquisa e Ensino\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.rededorsaoluiz.com.br\\\/instituto\\\/idor\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa - IDOR - Instituto D'Or de Pesquisa e Ensino","canonical":"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/","og_locale":"pt_BR","og_type":"article","og_title":"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa - IDOR - Instituto D'Or de Pesquisa e Ensino","og_url":"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/","og_site_name":"IDOR - Instituto D'Or de Pesquisa e Ensino","article_modified_time":"2026-07-08T15:17:04+00:00","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/","url":"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/","name":"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa - IDOR - Instituto D'Or de Pesquisa e Ensino","isPartOf":{"@id":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/#website"},"datePublished":"2026-07-08T15:14:49+00:00","dateModified":"2026-07-08T15:17:04+00:00","breadcrumb":{"@id":"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/ptbr.idor.org\/servicos-diagnosticos-e-de-apoio-a-pesquisa\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/"},{"@type":"ListItem","position":2,"name":"Servi\u00e7os Diagn\u00f3sticos e de Apoio \u00e0 Pesquisa"}]},{"@type":"WebSite","@id":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/#website","url":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/","name":"IDOR - Instituto D'Or de Pesquisa e Ensino","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"}]}},"_links":{"self":[{"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/pages\/28637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/comments?post=28637"}],"version-history":[{"count":1,"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/pages\/28637\/revisions"}],"predecessor-version":[{"id":28639,"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/pages\/28637\/revisions\/28639"}],"wp:attachment":[{"href":"https:\/\/www.rededorsaoluiz.com.br\/instituto\/idor\/wp-json\/wp\/v2\/media?parent=28637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}